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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: RHTHTSRKKH TLEQKTDTRE NPQEYPDFYD FSNAACRPST PALSRRTPSP SQGGYFGPDL YSHNKASPSG LKSAYLPGQT SPKKQEEARR EYPLSPDG
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 87%.
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。