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Invitrogen
BTBD7 Polyclonal Antibody
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产品信息
PA5-62784
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RHTHTSRKKH TLEQKTDTRE NPQEYPDFYD FSNAACRPST PALSRRTPSP SQGGYFGPDL YSHNKASPSG LKSAYLPGQT SPKKQEEARR EYPLSPDG
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 87%.
靶标信息
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BTB (POZ) domain containing 7; BTB/POZ domain-containing protein 7
基因别名: BTBD7; FUP1; KIAA1525
UniProt ID: (Human) Q9P203
Entrez Gene ID: (Human) 55727
