Bax (Apoptosis Marker) Monoclonal Antibody (SPM336)

protein binding lipid binding channel activity Hsp70 protein binding identical protein binding protein homodimerization activity protein heterodimerization activity chaperone binding BH3 domain binding

ovarian follicle development neuron migration leukocyte homeostasis T cell homeostatic proliferation B cell homeostasis B cell apoptotic process kidney development release of cytochrome c from mitochondria blood vessel remodeling myeloid cell homeostasis B cell negative selection B cell homeostatic proliferation positive regulation of B cell apoptotic process glycosphingolipid metabolic process regulation of nitrogen utilization apoptotic process cellular response to DNA damage stimulus mitochondrion organization germ cell development spermatogenesis nervous system development sex differentiation mitochondrial fusion cell proliferation negative regulation of cell proliferation male gonad development extrinsic apoptotic signaling pathway via death domain receptors intrinsic apoptotic signaling pathway in response to DNA damage apoptotic mitochondrial changes fertilization response to wounding response to toxic substance response to salt stress post-embryonic development response to ionizing radiation establishment or maintenance of transmembrane electrochemical gradient response to gamma radiation positive regulation of calcium ion transport into cytosol negative regulation of mitochondrial membrane potential hypothalamus development cerebral cortex development positive regulation of protein complex assembly negative regulation of protein binding endoplasmic reticulum calcium ion homeostasis negative regulation of endoplasmic reticulum calcium ion concentration release of matrix enzymes from mitochondria cellular response to stress regulation of mammary gland epithelial cell proliferation cellular response to unfolded protein cellular response to UV limb morphogenesis ectopic germ cell programmed cell death odontogenesis of dentin-containing tooth regulation of apoptotic process positive regulation of apoptotic process regulation of neuron apoptotic process negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process mitochondrial fragmentation involved in apoptotic process development of secondary sexual characteristics retinal cell programmed cell death positive regulation of developmental pigmentation negative regulation of fibroblast proliferation spermatid differentiation post-embryonic camera-type eye morphogenesis response to axon injury homeostasis of number of cells homeostasis of number of cells within a tissue epithelial cell proliferation positive regulation of developmental process protein insertion into mitochondrial membrane release of sequestered calcium ion into cytosol positive regulation of release of sequestered calcium ion into cytosol neuron apoptotic process establishment of localization in cell regulation of cell cycle regulation of mitochondrial membrane potential Sertoli cell proliferation retina development in camera-type eye apoptotic process involved in mammary gland involution positive regulation of apoptotic process involved in mammary gland involution vagina development calcium ion transport into cytosol intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress thymocyte apoptotic process intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of release of cytochrome c from mitochondria motor neuron apoptotic process apoptotic signaling pathway extrinsic apoptotic signaling pathway extrinsic apoptotic signaling pathway in absence of ligand intrinsic apoptotic signaling pathway execution phase of apoptosis fibril organization cellular response to virus regulation of mitochondrial membrane permeability involved in apoptotic process positive regulation of mitochondrial membrane permeability involved in apoptotic process apoptotic process involved in patterning of blood vessels apoptotic process involved in embryonic digit morphogenesis regulation of mitochondrial membrane permeability involved in programmed necrotic cell death positive regulation of apoptotic DNA fragmentation regulation of intracellular signal transduction positive regulation of IRE1-mediated unfolded protein response epithelial cell apoptotic process positive regulation of epithelial cell apoptotic process B cell receptor apoptotic signaling pathway positive regulation of reproductive process positive regulation of motor neuron apoptotic process regulation of apoptotic signaling pathway negative regulation of apoptotic signaling pathway positive regulation of intrinsic apoptotic signaling pathway