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Bethyl Laboratories
Bcl11b Polyclonal Antibody
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Bcl11b Antibody (IHC-00077) in IHC (P)
Detection of human Bcl11b by immunohistochemistry. Sample: FFPE section of human skin tumor. Antibody: Affinity purified rabbit anti-Bcl11b (Product # IHC-00077) used at a dilution of 1:500. Detection: DAB. staining using anti-rabbit IHC antibody (Product # A120-501P) at a dilution of 1:100.
产品信息
IHC-00077
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 850 and the C-terminus (residue 894) of human B-cell CLL/lymphoma 11B.
偶联物
形式
Liquid
浓度
0.25 mg/mL
规格
25 µg
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, X. tropicalis, Bovine, Dog, Rabbit, Guinea pig_10141, Pig, Orangutan, Monkey, Gorilla and Chimpanzee
靶标信息
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B cell CLL/lymphoma 11B; B-cell CLL/lymphoma 11B; B-cell CLL/lymphoma 11B (zinc finger protein); B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein; B-cell lymphoma/leukaemia 11B; B-cell lymphoma/leukemia 11B; BAF chromatin remodeling complex subunit BCL11B; BCL-11B; BCL11B, BAF complex component; BCL11B/TRDC fusion; COUP-TF-interacting protein 2; hRit1; Radiation-induced tumor suppressor gene 1 protein; zinc f; zinc finger protein hRit1 alpha
基因别名: ATL1; ATL1-alpha; ATL1-beta; ATL1-delta; ATL1-gamma; BCL11B; CTIP-2; CTIP2; hRIT1-alpha; IDDFSTA; IMD49; RIT1; SMARCM2; ZNF856B
UniProt ID: (Human) Q9C0K0
Entrez Gene ID: (Human) 64919
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
metal ion binding
sequence-specific double-stranded DNA binding
keratinocyte development
epithelial cell morphogenesis
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
apoptotic process
axonogenesis
negative regulation of cell proliferation
post-embryonic development
regulation of gene expression
regulation of keratinocyte proliferation
regulation of lipid metabolic process
striatal medium spiny neuron differentiation
commitment of neuronal cell to specific neuron type in forebrain
central nervous system neuron differentiation
post-embryonic camera-type eye development
T cell differentiation in thymus
T cell receptor V(D)J recombination
hematopoietic stem cell migration
odontogenesis of dentin-containing tooth
positive T cell selection
skin development
regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
alpha-beta T cell differentiation
thymus development
T cell apoptotic process
negative regulation of T cell apoptotic process
thymocyte apoptotic process
negative regulation of thymocyte apoptotic process
olfactory bulb axon guidance
lymphoid lineage cell migration into thymus
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