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Invitrogen
Beclin 1 Recombinant Rabbit Monoclonal Antibody (6W4G3)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-51469
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6W4G3
抗原
Recombinant protein (or fragment)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.85 mg/mL
规格
85 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: APG6; Bcl-2-interacting protein beclin; beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; Protein GT197
基因别名: 4921513J16Rik; 5430417M23Rik; Atg6; BECN1; GT197
UniProt ID: (Rat) Q91XJ1, (Mouse) O88597
Entrez Gene ID: (Rat) 114558, (Mouse) 56208
autophagosome assembly
mitophagy
response to hypoxia
autophagy
cellular response to nitrogen starvation
lysosome organization
negative regulation of cell proliferation
positive regulation of autophagy
positive regulation of macroautophagy
CVT pathway
response to vitamin E
response to drug
nucleophagy
late endosome to vacuole transport
neuron development
beta-amyloid metabolic process
regulation of catalytic activity
defense response to virus
response to other organism
negative regulation of cell death
cellular response to aluminum ion
cellular response to epidermal growth factor stimulus
positive regulation of mitophagy
cytokinesis
angiogenesis
cell cycle
mitotic metaphase plate congression
macroautophagy
regulation of cytokinesis
receptor catabolic process
cellular response to glucose starvation
negative regulation of apoptotic process
cell division
mitophagy in response to mitochondrial depolarization
positive regulation of attachment of mitotic spindle microtubules to kinetochore
negative regulation of reactive oxygen species metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
