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Invitrogen
Benzafibrate Recombinant Mouse Monoclonal Antibody (4H1)
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Benzafibrate Antibody (MA566622) in SDS-PAGE
SDS-PAGE characterization of Benzafibrate under reducing conditions. Lane M: Protein marker (kDa); Lane BZF: Purified Benzafibrate Recombinant Monoclonal (Product # MA566622). Benzafibrate showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-664.
产品信息
MA566622
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4H1
抗原
Conjugate of BZF hapten and KLH.
偶联物
形式
Liquid
浓度
8.1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Bezafibrate is a fibric acid derivative used primarily as an antihyperlipidemic agent. It functions as an agonist for all three peroxisome proliferator-activated receptor (PPAR) subtypes: PPAR-alpha, PPAR-gamma, and PPAR-delta. Activation of PPAR-alpha by bezafibrate leads to reduced triglyceride levels, while PPAR-gamma activation results in insulin sensitization and enhanced glucose metabolism. PPAR-delta activation promotes fatty acid metabolism. Bezafibrate's role in regulating lipid homeostasis, inflammation, cell differentiation, and proliferation has been studied in various contexts, including its hepatic antifibrotic effects. The drug's chemical structure is characterized by a chlorobenzoylamino-ethyl-phenoxy-methylpropionic acid moiety, which contributes to its lipid-regulating properties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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