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Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that is a well-known environmental carcinogen, primarily produced through incomplete combustion of organic materials. It is commonly found in air, water, soil, and sediments, and is present in cigarette smoke and grilled foods. BaP is known to induce chronic inflammation and fibrosis, particularly in the liver, leading to diseases such as nonalcoholic steatohepatitis (NASH) upon prolonged exposure. Structurally, BaP is characterized by its high molecular weight and stability, with recent studies revealing new polymorphs under high-pressure conditions. BaP's interaction with DNA can lead to mutagenic changes, posing significant health risks. Efforts to understand its microbial degradation are ongoing, aiming to mitigate its environmental impact.
仅用于科研。不用于诊断过程。未经明确授权不得转售。