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Invitrogen
Bone SialoProtein Polyclonal Antibody
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产品信息
PA5-79424
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human Bone Sialoprotein (17-34aa FSMKNLHRRVKIEDSEEN).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - IHC: Human Osteosarcoma Tissue.
靶标信息
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Bone sialoprotein 2; Bone sialoprotein II; BSP II; Cell-binding sialoprotein; integrin binding sialoprotein; Integrin-binding sialoprotein
基因别名: BNSP; BSP; BSP II; BSP-II; Bsp2; BSPII; IBSP; SP-II
UniProt ID: (Human) P21815, (Mouse) Q61711
Entrez Gene ID: (Human) 3381, (Mouse) 15891, (Rat) 24477
