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Invitrogen
Bordetella pertussis ptxA Polyclonal Antibody
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Bordetella pertussis ptxA Antibody (PA5-117607) in WB
Western Blot analysis of ptxA using Bordetella pertussis ptxA Polyclonal Antibody (Product # PA5-117607). All lanes: ptxA Antibody at 2 µg/mL + recombinant Bordella pertussis pertussis toxin subunit 1 100ng. Secondary: Goat polyclonal to rabbit IgG at 1:1,000 dilution. Predicted band size: 36 kDa. Observed band size: 36 kDa.
产品信息
PA5-117607
产品规格
种属反应
Bacteria
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Bordetella pertussis Pertussis toxin subunit 1 protein (35-269aa)
偶联物
形式
Liquid
浓度
2.1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody has been tested in direct-ELISA
靶标信息
S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD+ into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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