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Invitrogen
Bradykinin Polyclonal Antibody
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产品信息
PA1-85080
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Bradykinin peptide (RPPGFSPFR) conjugated to c.BSA
偶联物
形式
Liquid
浓度
5 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Rabbit anti Bradykinin antibody recognizes bradykinin and lys-bradykinin (kallidin).
靶标信息
Kininogen-1 (KNG1), also known as BDK or bradykinin, is a protein that in humans is encoded by the KNG1 gene. It is mapped to 3q27.3. The KNG1 gene uses alternative splicing to generate two different proteins - high - molecular - weight kininogen (HMWK) and low - molecular- weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, KNG1, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. In addition to that, KNG1 is a constituent of the blood coagulation system as well as the kinin-kallikrein system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-2-thiol proteinase inhibitor; bradykinin; Fitzgerald factor; High molecular weight kininogen; HMWK; Kininogen-1; Williams-Fitzgerald-Flaujeac factor
基因别名: BDK; BK; KNG; KNG1
UniProt ID: (Human) P01042
Entrez Gene ID: (Human) 3827
platelet degranulation
smooth muscle contraction
inflammatory response
negative regulation of cell adhesion
positive regulation of cytosolic calcium ion concentration
blood coagulation, intrinsic pathway
negative regulation of endopeptidase activity
negative regulation of blood coagulation
positive regulation of urine volume
positive regulation of renal sodium excretion
vasodilation
positive regulation of apoptotic process
negative regulation of proteolysis
