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Invitrogen
Briakinumab Recombinant Human Monoclonal Antibody
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产品信息
MA5-41782
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1, lambda
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human IL12B
偶联物
形式
Liquid
浓度
1.68 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Briakinumab is a human anti-IL-12 monoclonal antibody being developed for the treatment of a number of T-cell driven autoimmune diseases. It targets and neutralize interleukin-12 and interleukin-23, two proteins associated with inflammation, such as pro-inflammatory interleukins or tumor necrosis factor- alpha. Briakinumab represents a novel approach to treating psoriasis, Multiple Sclerosis, Crohn's Disease and other autoimmune and inflammatory disorders. As of 2011 pharmaceutical development for psoriasis has been discontinued in the U. S. and Europe. Briakinumab targets and neutralizes interleukin-12 and interleukin-23.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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