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Invitrogen
Bub3 Polyclonal Antibody
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产品信息
PA5-78889
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence in the middle region of human Bub3 (76-90aa DHQLKMHDLNTDQEN).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: HELA whole cell, A549 whole cell, JURKAT whole cell, COLO320 whole cell. IHC: Rat Testis Tissue, Human Mammary Cancer Tissue IHC-F: rat lung tissue. ICC/IF: A549 Cell, HELA Cell.
靶标信息
This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BUB3 budding uninhibited by benzimidazoles 3 homolog; BUB3 mitotic checkpoint protein; budding uninhibited by benomyl; budding uninhibited by benzimidazoles 3 homolog; mitotic checkpoint component; Mitotic checkpoint protein BUB3; OTTHUMP00000020682; testicular tissue protein Li 27; WD repeat type I transmembrane protein A72.5
基因别名: Aa2-050; AU019800; AU021329; AU043350; AW146323; BUB3; BUB3L; C78067; hBUB3
UniProt ID: (Human) O43684, (Mouse) Q9WVA3
Entrez Gene ID: (Human) 9184, (Mouse) 12237, (Rat) 361662
mitotic sister chromatid segregation
sister chromatid cohesion
mitotic spindle assembly checkpoint
attachment of spindle microtubules to kinetochore
anaphase-promoting complex-dependent catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
cell division
meiotic cell cycle
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
spindle assembly checkpoint
cell cycle
chromosome segregation
mitotic nuclear division
regulation of chromosome segregation
