Invitrogen

C/EBP alpha Polyclonal Antibody

查看其他23个C/EBP alpha抗体

问题与答案

问题与答案

问题与答案

Additional Information:

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抗体检测数据 (2)

C/EBP alpha Antibody in Western Blot (WB)

C/EBP alpha Antibody in Western Blot (WB)

图: 1 / 2

C/EBP alpha Antibody (PA5-26487) in WB

Western blot analysis of C/EBP alpha in mouse liver tissue lysates. Samples were incubated with C/EBP alpha polyclonal antibody (Product # PA5-26487). Lysates: 35 µg/lane. CEBPA (arrow).

C/EBP alpha Antibody in Western Blot (WB)

C/EBP alpha Antibody in Flow Cytometry (Flow)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

C/EBP alpha Antibody in Western Blot (WB) — Western blot analysis of C/EBP alpha in mouse liver tissue lysates. Samples were incubated with C/EBP alpha polyclonal antibody (Product # PA5-26487). Lysates: 35 µg/lane. CEBPA (arrow).

C/EBP alpha Antibody in Flow Cytometry (Flow) — Flow cytometry of C/EBP alpha in Hela cells (right histogram). Samples were incubated with C/EBP alpha polyclonal antibody (Product # PA5-26487) followed by FITC-conjugated goat-anti-rabbit secondary antibody. Negative control cell (left histogram).

Immunogen image

C/EBP alpha Polyclonal Antibody

Immunogen Image C/EBP alpha Polyclonal Antibody

产品信息

PA5-26487

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

-

流式细胞分析 (Flow)

1:10-1:50

-

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 304-330 amino acids from the C-terminal region of human CEBPA

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.36 mg/mL

144 µg

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

This antibody is predicted to react with bovine and rat based on sequence homology.

靶标信息

The C/EBP (CCAAT/enhancer binding protein) family of transcription factors--alpha, beta, delta, and epsilon)--are widely expressed proteins found in a variety of tissues. These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) that conforms to the consensus sequence (I/V/L) KXEP. One of the major roles of these transcription factors is that of metabolic regulation in liver and fat cells. Studies suggest that these transcription factors act in a cascade aiding in the development of the adipose cell. Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display different function in gene regulation. From a neurological standpoint, C/EBPs have been implicated in the mediation of nerve growth factor, altering synaptic plasticity, and mediation of inflammatory response in AD patients.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: C EBP; C/EBP alpha; CCAAT/enhancer binding protein (C/EBP), alpha; CCAAT/enhancer-binding protein alpha; OTTHUMP00000220269

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基因别名: C/EBP-alpha; C/ebpalpha; CBF-A; CEBP; CEBPA

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UniProt ID: (Mouse) P53566

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Entrez Gene ID: (Human) 1050, (Mouse) 12606

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transcription regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase I regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding kinase binding chromatin DNA binding identical protein binding protein homodimerization activity sequence-specific DNA binding protein heterodimerization activity RNA polymerase II sequence-specific DNA binding transcription factor binding HMG box domain binding STAT family protein binding DNA-binding transcription factor binding RNA polymerase I regulatory region DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding transcription coactivator activity transcription factor binding protein domain specific binding protein complex binding histone deacetylase binding transcription regulatory region DNA binding basic leucine zipper transcription factor

negative regulation of transcription from RNA polymerase II promoter liver development generation of precursor metabolites and energy transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase I promoter negative regulation of cell proliferation positive regulation of gene expression cytokine-mediated signaling pathway myeloid cell differentiation lung development granulocyte differentiation positive regulation of proteasomal ubiquitin-dependent protein catabolic process glucose homeostasis positive regulation of macrophage activation fat cell differentiation negative regulation of cell cycle negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of inflammatory response regulation of cell cycle lipid homeostasis interleukin-6-mediated signaling pathway white fat cell proliferation energy homeostasis integrated stress response signaling positive regulation of DNA-templated transcription, initiation urea cycle embryonic placenta development transcription from RNA polymerase II promoter mitochondrion organization Notch signaling pathway multicellular organism development cholesterol metabolic process macrophage differentiation regulation of cell proliferation positive regulation of fat cell differentiation positive regulation of osteoblast differentiation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase III promoter cell maturation inner ear development white fat cell differentiation brown fat cell differentiation cellular response to lithium ion cellular response to organic cyclic compound