Invitrogen

C/EBP beta Monoclonal Antibody (18F8)

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C/EBP beta Monoclonal Antibody (18F8)

产品信息

MA1-826

应用
建议稀释比
已发表文章

免疫印迹 (WB)

2 µg/mL
-

免疫细胞化学 (ICC/IF)

Assay-dependent
-

免疫沉淀 (IP)

Assay-dependent
-

其他PubMed (Misc)

-
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产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

18F8

抗原

Synthetic peptide corresponding to residues M(1) H R L L A W D A A C L P P P A A F P K L H(21) of mouse C/EBP beta.
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein G

保存液

PBS with 1mg/mL BSA

内含物

0.05% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2276066

产品详细信息

MA1-826 detects C/EBP beta protein in human, mouse, and rat samples. MA1-826 only detects the LAP* isoform of C/EBP beta.

MA1-826 has successfully been used in Western blot, immunofluorescent and immunoprecipitation procedures. By Western blot, this antibody detects a 37 kDa protein representing LAP* of C/EBP beta (N-terminus fragment) in transfected 293T cells.

The MA1-826 immunogen is a synthetic peptide corresponding to residues M(1) H R L L A W D A A C L P P P A A F P K L H(21) of mouse C/EBP beta. This peptide (Cat. # PEP-243) is available for use in neutralization and control experiments.

靶标信息

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: AGP/EBP; C EBP; C/EBP BETA; C/EBP-related protein 2; CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer-binding protein beta; IL-6DBP; interleukin 6-dependent DNA-binding protein; Interleukin-6-dependent-binding protein; LAP; LIP; Liver activator protein; Liver-enriched inhibitory protein; Liver-enriched transcriptional activator; Nuclear factor NF-IL6; nuclear factor of interleukin 6; nuclear factor-IL6; nuclear protein Il6; OTTMUSP00000017503; SF-B; Silencer factor B; TCF-5; Transcription factor 5; transcription factor C/EBP beta

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基因别名: C/EBP-beta; C/EBPbeta; CEBPB; CRP2; IL-6DBP; IL6DBP; LAP; LIP; NF-IL6; NF-M; Nfil6; PP9092; Sfb; TCF5

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UniProt ID: (Human) P17676, (Mouse) P28033, (Rat) P21272

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Entrez Gene ID: (Human) 1051, (Mouse) 12608, (Rat) 24253

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功能
RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding kinase binding histone acetyltransferase binding glucocorticoid receptor binding protein homodimerization activity histone deacetylase binding ubiquitin-like protein ligase binding protein heterodimerization activity sequence-specific DNA binding basic leucine zipper transcription factor
参与通路
ovarian follicle development embryonic placenta development granuloma formation regulation of transcription, DNA-templated transcription from RNA polymerase II promoter acute-phase response inflammatory response immune response memory neuron differentiation positive regulation of interleukin-4 production mammary gland epithelial cell proliferation response to endoplasmic reticulum stress T-helper 1 cell activation negative regulation of T cell proliferation defense response to bacterium negative regulation of neuron apoptotic process regulation of interleukin-6 biosynthetic process positive regulation of fat cell differentiation positive regulation of osteoblast differentiation regulation of osteoclast differentiation negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter brown fat cell differentiation mammary gland epithelial cell differentiation regulation of transcription involved in cell fate commitment intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress cellular response to lipopolysaccharide cellular response to amino acid stimulus cellular response to interleukin-1 cellular response to organic cyclic compound hepatocyte proliferation liver regeneration positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress transcription, DNA-templated cell differentiation response to lipopolysaccharide fat cell differentiation positive regulation of transcription, DNA-templated
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