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Invitrogen
C/EBP delta Polyclonal Antibody
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产品信息
PA5-34466
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
An 18 amino acid peptide near the carboxy terminus of human CEBPD
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
A suggested positive control is rat spleen tissue lysate.
PA5-34466 can be used with blocking peptide PEP-1508.
靶标信息
C/EBP delta are CCAAT enhancer binding proteins (CEBPs), a family of transcription factors that all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. At least six members of the family have been isolated and characterized to date (CEBP alpha to CEBP zeta). CEBPD is a leucine zipper (LZ) DNA-binding protein that regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. CEBPD is an important transcriptional activator in the regulation of genes involved in immune and inflammatory responses and has been reported to possess many tumor suppressor-like properties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C EBP; C/EBP delta; C/EBP-related protein 3; C/EBPdelta; CCAAT/enhancer binding protein (C/EBP), delta; CCAAT/enhancer-binding protein delta; NF-IL6-beta; Nuclear factor NF-IL6-beta; Transcription factor CELF
基因别名: C/EBP-delta; C/EBPd; CEBPD; CELF; CRP3; NF-IL6-beta
UniProt ID: (Human) P49716, (Mouse) Q00322, (Rat) Q03484
Entrez Gene ID: (Human) 1052, (Mouse) 12609, (Rat) 25695
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
basic leucine zipper transcription factor
transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
fat cell differentiation
positive regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
inner ear development
