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Invitrogen
C1 inhibitor Polyclonal Antibody
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产品信息
PA5-102467
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SERPING1(Accession P05155), corresponding to amino acid residues K341-F391.
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SERPING1.
靶标信息
C1-inhibitor (C1INH) functions as a regulator of the activation of the classical complement pathway and of the contact activation system of kinin generation and coagulation. Its primary biologically relevant target proteinases are C1r, C1s, coagulation factors XIa and XIIa, and plasma kallikrein. C1-inhibitor consists of one polypeptide chain and has a molecular mass of ~104 kDa. Serum concentration has been determined to 180 µg/mL.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C1 esterase inhibitor; C1 Inh; C1 inhibitor; C1-inhibiting factor; C1-inhibitor; C1Inh; complement component 1 inhibitor; epididymis secretory sperm binding protein; esterase inhibitor; IC1; plasma protease (C1) inhibitor precursor; Plasma protease C1 inhibitor; serine (or cysteine) peptidase inhibitor, clade G, member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary); serine (or cysteine) proteinase inhibitor, clade G, member 1; serine/cysteine proteinase inhibitor clade G member 1; Serpin G1; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_1; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_2; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_3; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_4; serpin peptidase inhibitor clade G member 1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; serpin peptidase inhibitor, clade G, member 1; SERPING1; unnamed protein product
基因别名: C1IN; C1INH; C1NH; HAE1; HAE2; SERPING1
UniProt ID: (Human) P05155, (Rat) Q6P734, (Mouse) P97290
Entrez Gene ID: (Human) 710, (Rat) 295703, (Mouse) 12258
negative regulation of complement activation, lectin pathway
blood coagulation
hemostasis
blood circulation
fibrinolysis
complement activation, classical pathway
aging
biological_process
negative regulation of endopeptidase activity
innate immune response
immune system process
negative regulation of peptidase activity
regulation of blood coagulation
negative regulation of complement activation
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