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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
EMSY is a regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Diseases associated with EMSY include Sporadic Breast Cancer and Breast Cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BRCA2-interacting transcriptional repressor EMSY; EMSY BRCA2-interacting transcriptional repressor; EMSY protein; EMSY, BRCA2-interacting transcriptional repressor; FLJ90741; protein EMSY; similar to EMSY protein
基因别名: 2310016L09Rik; AU019521; AU019557; C11orf30; EMSY; GL002
UniProt ID: (Mouse) Q8BMB0, (Human) Q7Z589
Entrez Gene ID: (Mouse) 233545, (Human) 56946, (Rat) 361607