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Abnova
C14ORF21 Polyclonal Antibody, MaxPab™
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C14ORF21 Antibody (H00161424-B01P) in WB
Western Blot analysis of C14orf21 expression in transfected 293T cell line (H00161424-T01) by C14orf21 MaxPab polyclonal antibody.
Lane 1: C14orf21 transfected lysate(58.96 KDa).
Lane 2: Non-transfected lysate.
Lane 1: C14orf21 transfected lysate(58.96 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00161424-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
C14orf21 (AAH25332.1, 1 a.a. approximately 536 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MGQGPRSPHK VGRRFPAGGK RGRGAKGSGR PLPGRKRQPW PPPDGRSEPA PDSHPHLSPE ALGYFRRALS ALKEAPETGE ERDLMVHNIM KEVETQALAL STNRTGSEML QELLGFSPLK PLCRVWAALR SNLRTVACHR CGVHVLQSAL LQLPRLLGSA AEEEEEEEEE DGKDGPTETL EELVLGLAAE VCDDFLVYCG DTHGSFVVRT LLQVLGGTIL ESERARPRGS QSSEAQKTPA QECKPADFEV PETFLNRLQD LSSSFLKDIA VFITDKISSF CLQVALQVLH RKLPQFCAHL CNAVIGYLNT RGSSVDGSPL LLFLRDQTSS RLLEQVLLVL EPPRLQSLFE EHLQGQLQTL AAHPIANFPL QRLLDAVTTP ELLSPVFEEL SPVLEAVLAQ GHPGVVIALV GACRRVGAYQ AKVLQLLLEA FHCAEPSSRQ VACVPLFATL MAYEVYYGLT EEEGAVPAEH QVAMAAARAL GDVTVLGSLL LQHLLHFSTP GLVLRSLGAL TGPQLLSLAQ SPGRKLLLSL GSRTRS
靶标信息
The C14orf21 gene, also known as SLIRP (SRA stem-loop interacting RNA binding protein), is located on chromosome 14 and encodes a mitochondrial protein involved in RNA processing. SLIRP is crucial for the stabilization and regulation of mitochondrial-encoded RNAs, which play a vital role in mitochondrial gene expression and overall mitochondrial function. The SLIRP protein interacts with RNA stem-loop structures, particularly those involved in the steroid receptor RNA activator (SRA), thereby regulating gene expression by modulating the activity of nuclear receptors. Defects in SLIRP can lead to impaired mitochondrial function, resulting in various clinical manifestations, including mitochondrial myopathy and other disorders related to mitochondrial dysfunction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NOP9 nucleolar protein homolog; Nucleolar protein 9; pumilio domain-containing protein C14orf21
基因别名: C14orf21; KIAA2021; NOP9
UniProt ID: (Human) Q86U38
Entrez Gene ID: (Human) 161424
