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Invitrogen
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Immunogen sequence: SLSEDPCPSQ KALDPAPLAR PSPAGSAQTS PELEHRVSLF NQKNQEGFTV FQIRPVIHFQ PTVPMLEDKF RSLESKEQKL HRV
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.
C15orf27 is a voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum. Despite the presence of a voltage-sensor segment, it does not form a functional ion channel and its precise role remains unclear. The protein undergoes both rapid and slow structural rearrangements in response to changes in voltage, and contains a zinc-binding site that can regulate the slow conformational transition.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HsHVRP1; hTMEM266; Hv1 related protein 1; HV1-related protein 1; Transmembrane protein 266; transmembrane protein C15orf27
基因别名: C15orf27; HVRP1; TMEM266
UniProt ID: (Human) Q2M3C6
Entrez Gene ID: (Human) 123591