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Invitrogen
C17orf71 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-55202
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SINCLFTVPA NQAFVYIVPG SQEEDPVGML LDQLRSHCTV KDPESLLVPA PLSGPRRYQV MRQHSRQQLS FHIDSSSSSS SGQLVDFTLR EFLWQHVELV LSKKGFDDSV GRNPQPSHFE LPTYQKWISA ASK
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
靶标信息
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Amplified in breast cancer gene 2 protein; FLJ10587; FLJ23205; Nonsense-mediated mRNA decay factor SMG8; Protein smg-8 homolog
基因别名: ABC2; C17orf71; SMG8
Entrez Gene ID: (Human) 55181
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