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Invitrogen
C19orf10 Polyclonal Antibody
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C19orf10 Antibody (PA5-106865) in IHC (P)
Immunohistochemistry analysis of C19orf10 in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with C19orf10 polyclonal antibody (Product # PA5-106865) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-106865
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MYDGF(Accession Q969H8), corresponding to amino acid residues S50-K100.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total C19orf10.
靶标信息
The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. IL-25 (also called SF20/IL-25) is a secreted bone marrow stroma-derived growth factor cytokine that is derived from Th2 T-cells. IL-25 belongs to the IL-17 cytokine family and is capable of amplifying allergic type inflammatory responses by its actions on other cell types. IL-25 binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation. Infusion of mice with IL-25 induces IL-4, IL-5, and IL-13 gene expression. IL-25 induced mice also develop epithelial cell hyperplasia, increased mucus secretion, and airway hyperreactivity, suggesting that IL-25 may be an important mediator of allergic disease via production of IL-4, IL-5, IL-13 and eotaxin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CS010; IL 25; IL 27; interleukin 25; interleukin 27 working designation; interleukin-25; Interleukin25; MYDGF; Myeloid-derived growth factor; R33729 1; R337291; similar to lymphocyte antigen 6 complex, locus E ligand; stromal cell-derived growth factor SF20; UPF0556 protein C19orf10; UPF0556 protein C19orf10 homolog
基因别名: C19orf10; D17Wsu104e; EUROIMAGE1875335; IL25; IL27; IL27w; Ly6elg; MYDGF; R33729_1; SF20
UniProt ID: (Human) Q969H8, (Mouse) Q9CPT4
Entrez Gene ID: (Rat) 501282, (Human) 56005, (Mouse) 28106
positive regulation of endothelial cell proliferation
positive regulation of angiogenesis
angiogenesis
positive regulation of protein phosphorylation
apoptotic process
positive regulation of phosphatidylinositol 3-kinase signaling
IRE1-mediated unfolded protein response
negative regulation of apoptotic process
positive regulation of MAPK cascade
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein kinase B signaling
cellular response to brefeldin A
