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Invitrogen
C19orf48 Polyclonal Antibody
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产品信息
PA5-59814
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human C19orf48. Recombinant protein control fragment (Product #RP-99147).
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MTVLEAVLEI QAITGSRLLS MVPGPARPPG SCWDPTQCTR TWLLSHTPRR RWISGLPR
Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 40%.
靶标信息
The C19orf48 gene, located on chromosome 19q13, encodes a protein involved in various biological processes, including its role as a minor histocompatibility antigen recognized by CD8+ T cells. This gene has been implicated in oncogenesis due to its elevated expression in certain cancer types, such as breast cancer, where it has been associated with poor prognosis. The non-synonymous single-nucleotide polymorphisms within C19orf48 contribute to differential T-cell recognition in donor and recipient cells, highlighting its significance in immune responses. Additionally, C19orf48 has been linked with SNORD88C, a small nucleolar RNA (snoRNA) that guides methylation of rRNA, further illustrating its involvement in cellular proliferation and metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: multidrug resistance-related protein
Entrez Gene ID: (Human) 84798
