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Abnova
C1RL Polyclonal Antibody, MaxPab™
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产品信息
H00051279-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
C1RL (AAI56781.1, 1 a.a. approximately 487 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPGPRVWGKY LWRSPHSKGC PGAMWWLLLW GVLQACPTRG SVLLAQELPQ QLTSPGYPEP YGKGQESSTD IKAPEGFAVR LVFQDFDLEP SQDCAGDSVT ISFVGSDPSQ FCGQQGSPLG RPPGQREFVS SGRSLRLTFR TQPSSENKTA HLHKGFLALY QTVAVNYSQP ISEASRGSEA INAPGDNPAK VQNHCQEPYY QAAAAGALTC ATPGTWKDRQ DGEEVLQCMP VCGRPVTPIA QNQTTLGSSR AKLGNFPWQA FTSIHGRGGG ALLGDRWILT AAHTVYPKDS VSLRKNQSVN VFLGHTAIDE MLKLGNHPVH RVVVHPDYRQ NESHNFSGDI ALLELQHSIP LGPNVLPVCL PDNETLYRSG LLGYVSGFGM EMGWLTTELK YSRLPVAPRE ACNAWLQKRQ RPEVFSDNMF CVGDETQRHS VCQGDSGSVY VVWDNHAHHW VATGIVSWGI GCGEGYDFYT KVLSYVDWIK GVMNGKN
靶标信息
Complement component 1, r subcomponent-like protein (C1rLP) is part of the complement system, primarily involved in innate immunity. Located on human chromosome 12p13.31, C1rLP is closely related to C1r, a serine protease component of the C1 complex in the classical pathway of complement activation. C1rLP shares structural similarities with C1r, featuring serine protease domains that are crucial for the proteolytic processing required to activate the complement cascade. The precise functional role of C1rLP remains under investigation, but it is hypothesized to act as a modulator of complement activation, potentially influencing immune cell behavior during inflammation or infection. The potential existence of several isoforms of C1rLP suggests diverse regulatory functions, which could impact processes like opsonization, pathogen clearance, and inflammation. Current research explores its relevance in immune response regulation, with implications for understanding autoimmune and inflammatory diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C1r-like protein; C1r-like serine protease analog protein; C1r-LP; CLSPa; Complement C1r subcomponent-like protein; complement C1r-like proteinase; complement component 1, r subcomponent-like
基因别名: C1r-LP; C1RL; C1RL1; C1RLP; CLSPA
UniProt ID: (Human) Q9NZP8
Entrez Gene ID: (Human) 51279
