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Invitrogen
C1orf165 Polyclonal Antibody
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C1orf165 Antibody (PA5-143071) in WB
Western Blot analysis of C1orf165 in Daudi (A), Human Tonsil (B), Human Spleen (C) and Mouse Spleen (D) lysates (35 µg protein in RIPA buffer) using C1orf165 Polyclonal Antibody (Product # PA5-143071) at 0.3 µg/mL incubated for 1 hour. Detected by chemiluminescence.
产品信息
PA5-143071
产品规格
种属反应
Human,
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence CKNEERREAKYNLQ (aa 408-421).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
靶标信息
C1orf165, also known as CFAP299 (Cilia and Flagella Associated Protein 299), is located on chromosome 1 and encodes a protein that is implicated in ciliary function and structure. CFAP299 is essential for the proper assembly and motility of cilia and flagella, structures that are vital for various cellular processes, including cell motility, fluid movement, and signal transduction. Mutations in CFAP299 have been linked to primary ciliary dyskinesia (PCD), which is characterized by chronic respiratory tract infections, abnormal positioning of internal organs (situs inversus), and infertility due to defective cilia and flagella movement. The protein has been shown to interact with other ciliary proteins and play a role in the regulation of dynein arms and microtubule structures necessary for ciliary beating.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BEN domain-containing protein 5
基因别名: 2310026E23Rik; BEND5; C1orf165
UniProt ID: (Human) Q7L4P6, (Mouse) Q8C6D4
Entrez Gene ID: (Human) 79656, (Mouse) 67621
