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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Peptide sequence: LGRRLLEQAH APWLWDDWGP AGSSEDSASS ESSGAGGPAP RCAPPSPPPP
Sequence homology: Dog: 79%; Human: 100%
Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle (PubMed:26562023). May play a role in embryonic development. May be required for proper cilia beating. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Centriole, cilia and spindle-associated protein
基因别名: C1orf96; CCSAP; CSAP
Entrez Gene ID: (Human) 126731