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MA1-40045 detects C1q from mouse samples.
MA1-40045 has been successfully used in immunohistochemistry (frozen), ELISA and immunofluorescence applications.
The MA1-40045 immunogen is mouse C1q component of the C1 complex.
C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Complement C1q subcomponent subunit A; Complement C1q subcomponent subunit B; Complement C1q subcomponent subunit C; complement component 1, q subcomponent, c polypeptide; complement component 1, q subcomponent, gamma polypeptide
基因别名: AI255395; AI385742; C1q; C1qa; C1qb; C1qc; C1qg; Ciqc
UniProt ID: (Mouse) P98086, (Mouse) P14106, (Mouse) Q02105
Entrez Gene ID: (Mouse) 12259, (Mouse) 12260, (Mouse) 12262