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Invitrogen
C2orf60 Polyclonal Antibody
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产品信息
PA5-61096
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KRVVLFSPRD AQYLYLKGTK SEVLNIDNPD LAKYPLFSKA RRYECSLEAG DVLFIPALWF HNVISEEFGV GVNIFWKHLP SECYDKTDTY GNKDPTAASR AAQILDRALK TLAELPEEYR DFYARRMV
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.
靶标信息
tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hTYW5; jmjC domain-containing protein C2orf60; tRNA wybutosine-synthesizing protein 5; tRNA yW-synthesizing enzyme 5; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase
基因别名: C2orf60; hTYW5; TYW5
UniProt ID: (Human) A2RUC4
Entrez Gene ID: (Human) 129450
