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Invitrogen
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Highest antigen sequence identity to the following orthologs: Mouse- 59%, Rat- 67%.
Sequence of this protein is as follows: EDKINVGGGL SGDHCKKFGG GKTERARKAM AVEDIISRVR GGSSGWSGGL AQNRSTITYR SWGRSLKYNP VVIDFEMQ
C8A is a component of the complement system and contains three polypeptide subunits: alpha, beta and gamma. C8A, in particular, contains the alpha subunit of C8 and is a constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. Disease associated with C8A include Type 1 C8 deficiency and immunodeficiency due to C8A deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Complement component 8 subunit alpha; Complement component C8 alpha chain
基因别名: C8A
Entrez Gene ID: (Human) 731