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Invitrogen
C9orf114 Polyclonal Antibody
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C9orf114 Antibody (PA5-116840) in IHC (P)
Immunohistochemistry analysis of C9orf114 in paraffin-embedded human liver cancer. Samples were incubated with C9orf114 Polyclonal antibody (Product # PA5-116840) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-116840
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 163-340 of human C9orf114 (NP_0574742)
偶联物
形式
Liquid
浓度
0.37 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: U-87MG, K-562
Immunogen sequence: HQDLQFAGLL NPLDSPHHMR QDEESEFREG IVVDRPTRPG HGSFVNCGMK KEVKIDKNLE PGLRVTVRLN QQQHPDCKTY HGKVVSSQDP RTKAGLYWGY TVRLASCLSA VFAEAPFQDG YDLTIGTSER GSDVASAQLP NFRHALVVFG GLQGLEAGAD ADPNLEVAEP SVLFDLYV
靶标信息
C9orf114 is a protein coding gene. Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Also involved in chromosome alignment. May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis. Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CENP-32; Centromere protein 32; Kinetochore-associated protein; Putative methyltransferase C9orf114; SPOUT domain-containing methyltransferase 1; uncharacterized protein C9orf114 homolog
基因别名: C9orf114; CENP-32; HSPC109; SPOUT1
UniProt ID: (Human) Q5T280
Entrez Gene ID: (Rat) 499770, (Human) 51490
