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Invitrogen
C9orf7 Polyclonal Antibody
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产品信息
PA5-110797
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: NAIAFATGVL YGLSALGKKG DAISYARIQQ QRQQADEEKL AETLE
Highest antigen sequence indentity to the following orthologs: Mouse - 98%, Rat - 98%.
靶标信息
Transmembrane protein which mediates synaptic endocytosis and fitness-based cell culling. In response to different stimulus strengths, controls two major modes of synaptic vesicle (SV) retrieval in hippocampal neurons; Clathrin- mediated endocytosis (CME) in response to mild stimulation and activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (By similarity). In cytotoxic T-lymphoocytes (CTLs) facilitates calcium-dependent endocytosis of cytotoxic granules at the immuno synapse (By similarity). Different isoforms work as fitness fingerprints in 'loser' and 'winner' cells and thereby mediate win/lose decisions as part of the cell competition process.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcium channel flower domain-containing protein 1; Calcium channel flower homolog
基因别名: C9orf7; CACFD1; D9S2135; FLOWER; PSEC0107; PSEC0248; UNQ3071/PRO9903
UniProt ID: (Human) Q9UGQ2
Entrez Gene ID: (Human) 11094
