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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: NAIAFATGVL YGLSALGKKG DAISYARIQQ QRQQADEEKL AETLE
Highest antigen sequence indentity to the following orthologs: Mouse - 98%, Rat - 98%.
Transmembrane protein which mediates synaptic endocytosis and fitness-based cell culling. In response to different stimulus strengths, controls two major modes of synaptic vesicle (SV) retrieval in hippocampal neurons; Clathrin- mediated endocytosis (CME) in response to mild stimulation and activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (By similarity). In cytotoxic T-lymphoocytes (CTLs) facilitates calcium-dependent endocytosis of cytotoxic granules at the immuno synapse (By similarity). Different isoforms work as fitness fingerprints in 'loser' and 'winner' cells and thereby mediate win/lose decisions as part of the cell competition process.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Calcium channel flower domain-containing protein 1; Calcium channel flower homolog
基因别名: C9orf7; CACFD1; PSEC0107; PSEC0248; UNQ3071/PRO9903
Entrez Gene ID: (Human) 11094