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Invitrogen
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Peptide sequence: LLEREEKEKL FNEHIEALTK KKREHFRQLL DETSAITLTS TWKEVKKIIK
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%; Zebrafish: 86%
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: co-activator of 150 kDa; MGC133200; TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD; TATA box-binding protein-associated factor 2S; Transcription elongation regulator 1; Transcription factor CA150
基因别名: CA150; TAF2S; TCERG1; Urn1
UniProt ID: (Human) O14776
Entrez Gene ID: (Human) 10915