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Invitrogen
CABLES1 Polyclonal Antibody
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CABLES1 Antibody (PA5-67978) in IHC (P)
Immunohistochemical analysis of CABLES1 in paraffin-embedded human small intestinal carcinoma tissue. 1) CABLES1 Polyclonal Antibody (Product # PA5-67978) was diluted at 1:200 (4° overnight). 2) Sodium citrate pH 6.0 was used for antigen retrieval (>98°C,20 min). 3) Secondary antibody was diluted at 1:233.
产品信息
PA5-67978
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from human CABLES1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted to react with Mouse samples.
靶标信息
Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cdk3-binding protein ik3-1; CDK5 and ABL1 enzyme substrate 1; Ik3-1; Interactor with CDK3 1; interactor-1 with cdk3
基因别名: CABL1; CABLES; CABLES1; HsT2563; IK3-1
UniProt ID: (Human) Q8TDN4, (Mouse) Q9ESJ1
Entrez Gene ID: (Human) 91768, (Mouse) 63955
