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Abnova
CACNA1F Monoclonal Antibody (3B2)
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产品信息
H00000778-M01J
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG3, kappa
分类
Monoclonal
类型
Antibody
克隆号
3B2
抗原
CACNA1F (NP_005174, 1878 a.a. approximately 1977 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: LHVPGTHSDP SHGKRGSADS LVEAVLISEG LGLFARDPRF VALAKQEIAD ACRLTLDEMD NAASDLLAQG TSSLYSDEES ILSRFDEEDL GDEMACVHAL
Cell culture grade monoclonal antibodies are obtained by purifying "hybridoma culture medium" which completely eliminates any contamination of mice. They have high affinity, high purity, and no contamination.
靶标信息
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium channel, voltage-dependent, L type, alpha 1F subunit; Voltage-dependent L-type calcium channel subunit alpha-1F; Voltage-gated calcium channel subunit alpha Cav1.4
基因别名: AIED; CACNA1F; CACNAF1; Cav1.4; Cav1.4alpha1; COD3; COD4; CORDX; CORDX3; CSNB2; CSNB2A; CSNBX2; JM8; JMC8; OA2
UniProt ID: (Human) O60840
Entrez Gene ID: (Human) 778
