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Invitrogen
CACNB2 Polyclonal Antibody
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CACNB2 Antibody (PA5-90894) in IHC (P)
Immunohistochemistry analysis of CACNB2 in paraffin-embedded human colon carcinoma. Samples were incubated with CACNB2 Polyclonal antibody (Product # PA5-90894) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-90894
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment).
偶联物
形式
Liquid
浓度
0.64 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Mouse heart; Cellular Location: Cell membrane, Cytoplasmic side, Peripheral membrane protein, sarcolemma
靶标信息
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAB1; CAB2; CACNLB1; Calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; CCHLB1; Lambert-Eaton myasthenic syndrome antigen B; MGC138502; MGC138504; MGC41896; myasthenic (Lambert-Eaton) syndrome antigen B; MYSB; Voltage-dependent L-type calcium channel subunit beta-2; voltage-gated calcium channel beta2 subunit transcript variant X13
基因别名: AW060387; CAB2; CACNB2; CACNLB2; CAVB2; Cavbeta2; Cchb2; MYSB
UniProt ID: (Human) Q08289, (Mouse) Q8CC27, (Rat) Q9QUU7
Entrez Gene ID: (Human) 783, (Mouse) 12296, (Rat) 116600
voltage-gated calcium channel activity
calcium channel regulator activity
calcium channel activity
protein binding
high voltage-gated calcium channel activity
protein kinase binding
protein domain specific binding
actin filament binding
phosphoprotein binding
voltage-gated calcium channel activity involved in cardiac muscle cell action potential
voltage-gated calcium channel activity involved in AV node cell action potential
voltage-gated ion channel activity
voltage-gated ion channel
chemical synaptic transmission
neuromuscular junction development
visual perception
positive regulation of calcium ion transport
cardiac conduction
calcium ion import
calcium ion transmembrane transport
membrane depolarization during AV node cell action potential
regulation of heart rate by cardiac conduction
establishment of protein localization to plasma membrane
membrane depolarization during atrial cardiac muscle cell action potential
regulation of voltage-gated calcium channel activity
positive regulation of high voltage-gated calcium channel activity
positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
transport
ion transport
calcium ion transport
regulation of ion transmembrane transport
