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Abnova
CACNG1 Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00000786-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CACNG1 (NP_000718.1, 1 a.a. approximately 222 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSQTKMLKVR VTLFCILAGI VLAMTAVVTD HWAVLSPHME HHNTTCEAAH FGLWRICTKR IPMDDSKTCG PITLPGEKNC SYFRHFNPGE SSEIFEFTTQ KEYSISAAAI AIFSLGFIIL GSLCVLLSLG KKRDYLLRPA SMFYAFAGLC ILVSVEVMRQ SVKRMIDSED TVWIEYYYSW SFACACAAFI LLFLGGLALL LFSLPRMPRN PWESCMDAEP EH
靶标信息
Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an alpha1 subunit, a beta subunit, a gamma subunit and an alpha2 delta subunit. The beta subunit is encoded by four genes, designated beta1-beta4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the alpha1 subunit. L-type Ca ++ CP gamma1, also known as CACNLG or CACNG1, is a 222 amino acid multi-pass membrane protein belonging to the PMP-22/EMP/MP20 family. Expressed in skeletal muscle, L-type Ca ++ CP gamma1 is a subunit of the dihydropyridine (DHP) sensitive calcium channel and may play a role in excitation-contraction coupling. L-type Ca++ CP gamma1 is considered a novel marker for malignant hyperthermia susceptibility (MHS), an autosomal dominant disorder of skeletal muscle which manifests as a life-threatening hypermetabolic crisis triggered by commonly used inhalation anesthetics and depolarizing muscle relaxants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma; Voltage-dependent calcium channel gamma-1 subunit
基因别名: CACNG1; CACNLG
Entrez Gene ID: (Human) 786
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
