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Abnova
CACNG3 Polyclonal Antibody, MaxPab™
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产品信息
H00010368-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CACNG3 (NP_006530.1, 1 a.a. approximately 315 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRMCDRGIQM LITTVGAFAA FSLMTIAVGT DYWLYSRGVC RTKSTSDNET SRKNEEVMTH SGLWRTCCLE GAFRGVCKKI DHFPEDADYE QDTAEYLLRA VRASSVFPIL SVTLLFFGGL CVAASEFHRS RHNVILSAGI FFVSAGLSNI IGIIVYISAN AGDPGQRDSK KSYSYGWSFY FGAFSFIIAE IVGVVAVHIY IEKHQQLRAK SHSEFLKKST FARLPPYRYR FRRRSSSRST EPRSRDLSPI SKGFHTIPST DISMFTLSRD PSKITMGTLL NSDRDHAFLQ FHNSTPKEFK ESLHNNPANR RTTPV
靶标信息
Calcium Channel gamma-3 is a member of voltage dependent calcium channels (VDCCs) which allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal, and important in the genesis of synaptic transmission in discrete hippocampal fields. Calcium Channel gamma-3 is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. Further, Calcium Channel gamma-3 is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. Calcium Channel gamma-3 gene dysfunction is a susceptibility locus for childhood absence epilepsy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CACNLB3; calcium channel, voltage-dependent, gamma subunit 3; CaVgamma3; Neuronal voltage-gated calcium channel gamma-3 subunit; TARP gamma-3; Transmembrane AMPAR regulatory protein gamma-3; Voltage-dependent calcium channel gamma-3 subunit; voltage-gated calcium channel gamma subunit
基因别名: CACNG3
UniProt ID: (Human) O60359
Entrez Gene ID: (Human) 10368
