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Invitrogen
CAF1 p60 Polyclonal Antibody
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CAF1 p60 Antibody (PA5-92855) in IHC (P)
Immunohistochemistry analysis of CAF1 p60 in paraffin-embedded rat fallopian tube. Samples were incubated with CAF1 p60 Polyclonal antibody (Product # PA5-92855) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-92855
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 270-559 of human p60 CAF1 (NP_0054321)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.64 mg/mL
规格
64 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SRKNLKRPIA HLPCPGKATL AVRCCPVYFE LRPVVETGVE LMSLPYRLVF AVASEDSVLL YDTQQSFPFG YVSNIHYHTL SDISWSSDGA FLAISSTDGY CSFVTFEKDE LGIPLKEKPV LNMRTPDTAK KTKSQTHRGS SPGPRPVEGT PASRTQDPSS PGTTPPQARQ APAPTVIRDP PSITPAVKSP LPGPSEEKTL QPSSQNTKAH PSRRVTLNTL QAWSKTTPRR INLTPLKTDT PPSSVPTSVI STPSTEEIQS ETPGDAQGSP PELKRPRLDE NKGGTESLDP; Positive Samples: HeLa, 293T, MCF7, U-251MG; Cellular Location: Cytoplasm, Nucleus
靶标信息
Chromatin assembly factor 1 (CAF-1) is a member of the histone chaperone family. It is required for inheritance of epigenetically determined chromosomal states, and in vitro, it promotes the assembly of chromatin during DNA replication and DNA repair. CAF-1 is a complex of three subunits; p150, p60, and p48. This complex is localized to the nucleus of human cells. Both the composition and the biochemical activity of CAF-1 are conserved among human, yeast, and Drosophila.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAF-1 subunit B; CAF-I 60 kDa subunit; CAF1 p60; Chromatin assembly factor 1 subunit B; Chromatin assembly factor I p60 subunit; p60 CAF1; p60-CAF1
基因别名: 2600017H24Rik; C76145; CAF-I p60; CAF-Ip60; CAF1; CAF1A; CAF1P60; Chaf1b; MPHOSPH7
UniProt ID: (Mouse) Q9D0N7
Entrez Gene ID: (Mouse) 110749, (Rat) 288242
positive regulation of defense response to virus by host
DNA replication
DNA repair
nucleosome assembly
DNA replication-dependent nucleosome assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
cell cycle
chromatin assembly
mitophagy in response to mitochondrial depolarization
reproduction
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