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Agrisera
CALS12/PMR4/Callose synthase 12 Polyclonal Antibody
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CALS12/PMR4/Callose synthase 12 Antibody (AS21-4567) in WB
Samples: 1:Col-0 – Total protein extract 2:pmr 4-1/cals 12 – Total protein extract 3:Col-0 – soluble protein fraction (S 100) 4:pmr 4-1/cals 12 – soluble protein fraction (S 100) 5:Col-0 – microsomal protein fraction (P 100/M) 6:pmr 4-1/cals 12 – microsomal protein fraction (P 100/M) Total proteins were isolated from 60 Arabidopsis thaliana seedlings (10-day-old) of Col-0 (wild- type; lanes 1,3,5) and pmr 4... View More
产品信息
AS21-4567
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated peptide derived from Arabidopsis thaliana CALS12 protein sequence.
偶联物
形式
Lyophilized
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
靶标信息
CALS12 encodes a large integral membrane callose synthase that localizes predominantly to the plasma membrane (and is also reported in Golgi-associated fractions), where it functions within a 1,3-beta-D-glucan synthase complex to polymerize callose for deposition at the cell wall-plasma membrane interface and at plasmodesmata. The protein is predicted to be multi-pass, with multiple C-terminal transmembrane helices anchoring a substantial cytosolic catalytic region characteristic of glucan synthase-like/glycosyltransferase enzymes. Biologically, CALS12-dependent callose accumulation contributes to regulated cell-to-cell connectivity by modulating plasmodesmatal permeability and reinforces local wall barriers during stress; genetic and physiological studies support key roles in inducible callose deposition during pathogen challenge (impacting penetration resistance and defense signaling outputs) and in adaptive responses such as phosphate deficiency, where CALS12 is required for callose deposition in root hairs that supports phosphate acquisition and growth under low-phosphate conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATGSL05; ATGSL5; EED3; enhancer of edr1 3; GLUCAN SYNTHASE-LIKE 5; GSL5; PMR4; POWDERY MILDEW RESISTANT 4; T5L23.4
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