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Invitrogen
CAMK2N1 Polyclonal Antibody
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产品信息
PA5-23740
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 37-65 amino acids from the C-terminal region of human CAMK2N1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine and rat based on sequence homology.
靶标信息
Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity). Plays a role in the maintenance of long-term retrieval- induced memory in response to contextual fear (By similarity). Modulates blood pressure and vascular reactivity via regulation of CAMK2 activity in addition to regulation of left ventricular mass (By similarity). Mediates the NLRP3 inflammasome in cardiomyocytes via acting as an inhibitor of the MAPK14/p38 and MAPK8/JNK pathways, thereby regulating ventricular remodeling and cardiac rhythm post- myocardial infarction (By similarity). Negatively effects insulin sensitivity and promotes lipid formation in adipose tissues independent of CAMK2 signaling (By similarity).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Calcium/calmodulin-dependent protein kinase II inhibitor 1; calcium/calmodulin-dependent protein kinase II inhibitor alpha; CaMKII inhibitor protein alpha; CaMKII inhibitory protein alpha; CaMKIIN-alpha; CaMKIINalpha; mCaMKIINalpha; RP11-401M16.1
基因别名: 1810006K23Rik; AI848599; AI891706; CAMK2N1; PRO1489
UniProt ID: (Human) Q7Z7J9, (Mouse) Q6QWF9
Entrez Gene ID: (Human) 55450, (Mouse) 66259
