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Abnova
CAND1 Monoclonal Antibody (1G5)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00055832-M05
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG3, kappa
分类
Monoclonal
类型
Antibody
克隆号
1G5
抗原
CAND1 (NP_060918, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5-1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MASASYHISN LLEKMTSSDK DFRFMATNDL MTELQKDSIK LDDDSERKVV KMILKLLEDK NGEVQNLAVK CLGPLVSKVK EYQVETIVDT LCTNMLSDKE
靶标信息
CAND1 enhances transcription from various types of promoters. It is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site. CAND1 disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cullin associated and neddylation disassociated 1; cullin-associated and neddylation-dissociated protein 1; DKFZp434M1414; FLJ10114; FLJ10929; FLJ38691; FLJ90441; p120 CAND1; TBP-interacting protein; TBP-interacting protein 120A; TBP-interacting protein of 120 kDa A; TBP-interacting protein TIP120A; unnamed protein product
基因别名: 2310038O07Rik; 6330512O03Rik; D10Ertd516e; mKIAA0829; TIP120; TIP120A; Tp120a
UniProt ID: (Human) Q86VP6, (Rat) P97536, (Mouse) Q6ZQ38
Entrez Gene ID: (Human) 55832, (Rat) 117152, (Mouse) 71902
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
