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CARF Monoclonal Antibody (2E6)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00055602-M04
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
2E6
抗原
CARF (AAH22270, 1 a.a. approximately 579 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MAQEVSEYLS QNPRVAAWVE ALRCDGETDK HWRHRRDFLL RNAGDLAPAG GAASASTDEA ADAESGTRNR QLQQLISFSM AWANHVFLGC RYPQKVMDKI LSMAEGIKVT DAPTYTTRDE LVAKVKKRGI SSSNEGVEEP SKKRVIEGKN SSAVEQDHAK TSAKTERASA QQENSSTCIG SAIKSESGNS ARSSGISSQN SSTSDGDRSV SSQSSSSVSS QVTTAGSGKA SEAEAPDKHG SSFVSLLKSS VNSHMTQSTD SRQQSGSPKK SALEGSSASA SQSSSEIEVP LLGSSGSSEV ELPLLSSKPS SETASSGLTS KTSSEASVSS SVAKNSSSSG TSLLTPKSSS STNTSLLTSK STSQVAASLL ASKSSSQTSG SLVSKSTSLA SVSQLASKSS SQTSTSQLPS KSTSQSSESS VKFSCKLTNE DVKQKQPFFN RLYKTVAWKL VAVGGFSPNV NHGELLNAAI EALKATLDVF FVPLKELADL PQNKSSQESI VCELRCKSVY LGTGCGKSKE NAKAVASREA LKLFLKKKVV VKICKRKYRG SEIEDLVLLD EESRPVNLPP ALKHPQELL
靶标信息
CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDKN2A-interacting protein; Collaborator of ARF
基因别名: CARF; CDKN2AIP
Entrez Gene ID: (Human) 55602
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
