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NeoBiotechnologies
CARM1 Monoclonal Antibody (CARM1/7426)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
10498-MSM3-P0
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
CARM1/7426
抗原
Recombinant fragment (around aa200-400) of human CARM1 protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
200 µg/mL
规格
20 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4°C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: protein arginine N-methyltransferase 4
基因别名: PRMT4
UniProt ID: (Human) Q86X55
Entrez Gene ID: (Human) 10498
transcription regulatory region sequence-specific DNA binding
transcription coactivator activity
protein binding
beta-catenin binding
protein methyltransferase activity
protein-arginine N-methyltransferase activity
protein-arginine omega-N asymmetric methyltransferase activity
histone methyltransferase activity (H3-R17 specific)
histone methyltransferase activity
histone methyltransferase activity (H3-R2 specific)
DNA-binding transcription factor binding
chromatin remodeling
regulation of transcription, DNA-templated
positive regulation of cell proliferation
regulation of intracellular estrogen receptor signaling pathway
positive regulation of fat cell differentiation
positive regulation of transcription from RNA polymerase I promoter
response to cAMP
replication fork reversal
positive regulation of epithelial cell apoptotic process
negative regulation of dendrite development
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