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Rockland
CAV3.2 Monoclonal Antibody (N55/10)
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CAV3.2 Antibody (200-301-F11) in IHC (F)
Immunohistochemistry of Mouse anti-Cav3.2 antibody. Tissue: mouse brain extract. Fixation: Frozen. Primary Antibody: anti-Cav 3.2 antibody at 1 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase mouse secondary at 1:10,000 for 45 min at RT. Localization: Membrane. Staining: Cav 3.2 as precipitated brown signal.
产品信息
200-301-F11
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N55/10
抗原
Cav3.2 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to an internal region (II-III loop) of human Cav3.2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A1H-b; calcium channel alpha13.2 subunit; calcium channel, voltage-dependent, T type, alpha 1H subunit; calcium channel, voltage-dependent, T type, alpha 1Hb subunit; FLJ90484; Low-voltage-activated calcium channel alpha1 3.2 subunit; low-voltage-activated calcium channel alpha13.2 subunit; T-type Cav3.2; voltage dependent t-type calcium channel alpha-1H subunit; Voltage-dependent T-type calcium channel subunit alpha-1H; voltage-gated calcium channel alpha subunit Cav3.2; voltage-gated calcium channel alpha subunit CavT.2; Voltage-gated calcium channel subunit alpha Cav3.2
基因别名: alpha13.2; CACNA1H; CACNA1HB; Cav3.2; ECA6; EIG6; MNCb-1209
UniProt ID: (Human) O95802, (Rat) Q9EQ60
Entrez Gene ID: (Human) 8912, (Rat) 114862, (Mouse) 58226
transport
muscle contraction
muscle organ development
myoblast fusion
regulation of heart contraction
aldosterone biosynthetic process
cellular response to hormone stimulus
cortisol biosynthetic process
regulation of ion transmembrane transport
cellular response to potassium ion
regulation of membrane potential
calcium ion import
calcium ion transmembrane transport
membrane depolarization during action potential
positive regulation of acrosome reaction
calcium ion transport
sensory perception of pain
positive regulation of calcium ion-dependent exocytosis
ion transport
ion transmembrane transport
transmembrane transport
