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Abnova
CBX6 Polyclonal Antibody, MaxPab™
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产品信息
H00023466-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CBX6 (AAH12111.1, 1 a.a. approximately 412 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MELSAVGERV FAAESIIKRR IRKGRIEYLV KWKGWAIKYS TWEPEENILD SRLIAAFEQK ERERELYGPK KRGPKPKTFL LKARAQAEAL RISDVHFSVK PSASASSPKL HSSAAVHRLK KDIRRCHRMS RRPLPRPDPQ GGSPGLRPPI SPFSETVRII NRKVKPREPK RNRIILNLKV IDKGAGGGGA GQGAGALARP KVPSRNRVIG KSKKFSESVL RTQIRHMKFG AFALYKPPPA PLVAPSPGKA EASAPGPGLL LAAPAAPYDA RSSGSSGCPS PTPQSSDPDD TLPKLLPETV SPSAPSWREP EVLDLSLPPE SAATSKRAPP EVTAAAGPAP PTAPEPAGAS SEPEAGDWRP EMSPCSNVVV TDVTSNLLTV TIKEFCNPED FEKVAAGVAG AAGGGGSIGA SK
靶标信息
Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex. Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes. Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRromatin Organization MOdifier) domain. This domain plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: chromobox homolog 6; Chromobox protein homolog 6
基因别名: CBX6
UniProt ID: (Human) O95503
Entrez Gene ID: (Human) 23466
