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Invitrogen
CC2D1A Polyclonal Antibody
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产品信息
PA5-52141
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: NLLASIRKGN AIDEADIPPP VAIGKGPAST PTYSPAPTQP APRIASAPEP RVTLEGPSAT APASSPGLAK PQMPPGPCSP GPLAQLQSRQ RDYKLAALHA KQQGDTTAAA RHFRVAKSFD AVLE
Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 60%.
靶标信息
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Akt kinase-interacting protein 1; Coiled-coil and C2 domain-containing protein 1A; Five prime repressor element under dual repression-binding protein 1; five repressor element under dual repression-binding protein 1; FLJ20241; FRE under dual repression-binding protein 1; mental retardation, nonsyndromic, autosomal recessive, 3; Putative NF-kappa-B-activating protein 023N; putative NFkB activating protein
基因别名: AKI1; CC2D1A; FREUD-1; Freud-1/Aki1; LGD2; MRT3
UniProt ID: (Human) Q9H603
Entrez Gene ID: (Human) 54862
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
signal transducer activity
protein binding
cadherin binding involved in cell-cell adhesion
