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Invitrogen
CC2D1A Recombinant Rabbit Monoclonal Antibody (JE55-34)
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CC2D1A Antibody (MA5-42503) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human appendix tissue using CC2D1A Recombinant Monoclonal Antibody (Product # MA5-42503). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the CC2D1A antibody a... View More
产品信息
MA5-42503
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JE55-34
抗原
Recombinant protein within C-terminal Human CC2D1A
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: MCF-7 cell lysate, A431 cell lysate, PC-12 cell lysate, human appendix tissue, human tonsil tissue, MCF-7.
Subcellular Location: Centrosome, Nucleus, Cytoplasm.
靶标信息
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Akt kinase-interacting protein 1; Coiled-coil and C2 domain-containing protein 1A; Five prime repressor element under dual repression-binding protein 1; five repressor element under dual repression-binding protein 1; FLJ20241; FRE under dual repression-binding protein 1; freud-1; mental retardation, nonsyndromic, autosomal recessive, 3; Putative NF-kappa-B-activating protein 023N; putative NFkB activating protein
基因别名: AKI1; CC2D1A; FREUD-1; Freud-1/Aki1; LGD2; MRT3; RGD1306108
UniProt ID: (Human) Q9H603, (Rat) Q66HA5
Entrez Gene ID: (Human) 54862, (Rat) 288908
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
signal transducer activity
protein binding
cadherin binding involved in cell-cell adhesion
