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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SNEHTAEMEH MKSLVHRLFT ILHLEESQKK REHHLLEKID HLKEQLQPLE QVKAGIEAHS E
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%.
Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Calcium uniporter regulatory subunit MCUb, mitochondrial; Coiled-coil domain-containing protein 109B; MCUb
基因别名: CCDC109B; MCUB
Entrez Gene ID: (Human) 55013