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Invitrogen
CCDC90A Polyclonal Antibody
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CCDC90A Antibody (PA5-95628) in IHC (P)
Immunohistochemistry analysis of CCDC90A in paraffin-embedded human esophagus squama cancer tissue. Antigen retrieval was performed on the tissue using citrate buffer (pH 6, 20 min) and blocked with 10% goat serum. Samples were incubated with CCDC90A polyclonal antibody (Product # PA5-95628) at a 1 µg/mL dilution, followed by biotinylated goat anti-rabbit IgG (30 min, 37°C), and developed with Strepavidin-B... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-95628
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence of human MCUR1 (ATQQAEIIVSALVKILEANMDIVYKDMVTKMQQE).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cellhuman MDA-MB-231 whole cell, human HL-60 whole cell, human MDA-MB-453 whole cell, human A431 whole cell, human Caco-2 whole cell, rat spleen tissue, mouse lung tissue, mouse Ana-1 whole cell. IHC: human oesophagus squama cancer tissue, human ovary cancer tissue, human lung cancer tissue, human placenta tissue, human tonsil tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
Mcur1 encodes a protein that is a key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion. Mcur1 plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU (mitochondrial calcium uniporter). Mcur1 may be involved in the assembly of the membrane components of the uniporter complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: coiled-coil domain containing 90A; Coiled-coil domain-containing protein 90A, mitochondrial; epididymis secretory sperm binding protein; MCU regulator 1; MCURI1; Mitochondrial calcium uniporter regulator 1; unnamed protein product
基因别名: 6230416A05Rik; AU015498; AV136929; AW554392; C6orf79; C88263; CCDC90A; FMP32; MCUR1; RGD1307673
UniProt ID: (Human) Q96AQ8, (Mouse) Q9CXD6
Entrez Gene ID: (Human) 63933, (Mouse) 76137, (Rat) 291034
transport
ion transport
calcium ion transport
mitochondrial calcium ion transport
positive regulation of mitochondrial calcium ion concentration
calcium ion import
generation of precursor metabolites and energy
cell proliferation
cell migration
calcium ion transmembrane import into mitochondrion
protein heterooligomerization
establishment of localization in cell
calcium ion transmembrane transport
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