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Bethyl Laboratories
CCDC94 Polyclonal Antibody
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CCDC94 Antibody (A305-882A-T) in WB
Detection of human CCDC94 by western blot. Samples: Whole cell lysate (50 µg) from HEK293T, K-562, and MCF-7 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CCDC94 antibody A305-882A-M (lot A305-882A-M-1) used for WB at 1:1000. Detection: Chemiluminescence with an exposure time of 3 minutes.
产品信息
A305-882A-T
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A region between residue 273 and 323 of human Coiled-coil domain-containing protein 94.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7.0 to 8.0
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA (PubMed:29301961). Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex (PubMed:22952453). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Coiled-coil domain-containing protein 94; Splicing factor YJU2
基因别名: CCDC94; YJU2
UniProt ID: (Human) Q9BW85
Entrez Gene ID: (Human) 55702
