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Invitrogen
CCDC94 Polyclonal Antibody
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产品信息
PA5-60435
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ITFKTDPENT DYTMEHGATR NFQAEKLLEE EEKRVQKERE DEELNNPMKV LENRTKDSKL EMEVLENLQE LK
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
靶标信息
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA (PubMed:29301961). Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex (PubMed:22952453). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Coiled-coil domain-containing protein 94; Splicing factor YJU2
基因别名: 2900016D05Rik; AI413813; CCDC94; YJU2
UniProt ID: (Human) Q9BW85, (Mouse) Q9D6J3
Entrez Gene ID: (Human) 55702, (Mouse) 72886
