Search Thermo Fisher Scientific
PA1-29031 detects CCL21 from rat samples.
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 6 Ckine; C-C motif chemokine 21; chemokine (C-C motif) ligand 21b (serine); small inducible cytokine A21
基因别名: Ccl21b
Entrez Gene ID: (Rat) 298006
分子生物学功能: cytokine intercellular signal molecule